Skip to content
Quick view
Quick view
$110.00
$114.90
-4%
View full details Link chevron
Features Plus

A herbal formula that may assist in maintaining healthy stress response and reduce behavioural issues associated to high stress contexts in dogs and cats. It uses a combination of herbs that work synergistically together to support the central nervous system in times of stress. This is a proprietary blends that has been used on many dogs and cats to help them cope better in their day-to-day living situations where stress may be a factor.

May help to:

  • Decrease over arousal behaviours (hyper-excitability)
  • Support return to normal sleep patterns
  • Provide support to the central nervous system in times of stress such as storms, travel, house guests, training, car travel

We have paired this with a probiotic to further support to the digestive system and support a healthy serotonin production, helpful in further reducing adverse stress responses.

Ingredients Plus

Pet-Destress

Skullcap (Scutellaria lateriflora), St. Johns Wort (Hypericum perforatum), Hops (Humulus lupulus),Passionflower (Passiflora incarnata),Lemon Balm (Melissa officinalis),Lavender (Lavandula), Chamomile (Matricaria chamomilla), Valerian (Valeriana officinalis), Vervain (Verbena),Water(H2O), Ethanol (C2H6O)

Multi-strain Probiotic

Each gram contains: 60 million CFU of Lactobacillus Acidophilus, L Delbruekii, L Plantarum, L Rhamnosus, Bifidobacterum bifidum, Enterococcus faecium, Streptococcus salivarius. 

Directions & Storage Plus

Store below 25 degrees Celsius. Keep in a cool dry place out of direct sunlight. Keep container tightly closed.Keep out of reach of children.

Cautions Plus

May have additive effects with medications that have sedative or anxiolytic effects. Professional veterinary supervision advised.

Discontinue 7 days prior to general anaesthesia or procedure when a sedative may be administered.

Do not give to pets on the following: cyclosporin, tacrolimus, omeprazole, methadone.

Do not give during pregnancy and lactation without professional veterinary supervision.

The Science Plus

Alex, A., Srivastava, A. (2019). Nutraceuticals for Calming and Stress. In: Gupta, R., Srivastava, A., Lall, R. (eds) Nutraceuticals in Veterinary Medicine. Springer, Cham. https://doi.org/10.1007/978-3-030-04624-8_27

Awad, R., Arnason, J. T., Trudeau, V., Bergeron, C., Budzinski, J. W., Foster, B. C., & Merali, Z. (2003). Phytochemical and biological analysis of skullcap (Scutellaria lateriflora L.): a medicinal plant with anxiolytic properties. Phytomedicine, 10(8), 640-649.

Binks, J., Taylor, S., Wills, A., & Montrose, V. T. (2018). The behavioural effects of olfactory stimulation on dogs at a rescue shelter. Applied Animal Behaviour Science, 202, 69–76. https://doi.org/10.1016/j.applanim.2018.01.009

Bol S, Caspers J, Buckingham L et al. (2017). Responsiveness of cats (Felidae) to silver vine (Actinidia polygama), Tatarian honeysuckle (Lonicera tatarica), valerian (Valeriana officinalis) and catnip (Nepeta cataria). BMC Vet Res, 13 (1), 1-15.

Fonseca LRd, Rodrigues R de A, Ramos A de S et al. (2020). Herbal Medicinal Products from Passiflora for Anxiety: An Unexploited Potential. Sci World J, 2020, 6598434.

Goodwin S, Reynolds H (2018). Can aromatherapy be used to reduce anxiety in hospitalised felines. The Veterinary Nurse, 9 (3), 167-171.

IONIȚĂ, R., Postu, P. A., CIOANCĂ, O., Mircea, C., HĂNCIANU, M., & HRIȚCU, L. (2019). Anxiolytic and antidepressant effects of Matricaria chamomilla hydroalcoholic extract in a rat model of scopolamine. Medicine, 67, 1.

Jawna‐Zboińska, K., Blecharz‐Klin, K., Joniec‐Maciejak, I., Wawer, A., Pyrzanowska, J., Piechal, A., ... & Widy‐Tyszkiewicz, E. (2016). Passiflora incarnata L. improves spatial memory, reduces stress, and affects neurotransmission in rats. Phytotherapy Research, 30(5), 781-789.

Rahmati B, Kiasalari Z, Roghani M, Khalili M, Ansari F (2017). Antidepressant and anxiolytic activity of Lavandula officinalis aerial parts hydroalcoholic extract in scopolamine-treated rats. Pharm Biol, 55 (1), 958-965.

Rezaie A, Pashazadeh M, Ahmadizadeh C, Jafari B, Jalilzadeh H. Study of Sedative and Anxiolytic Effect of Herbal Extract of Nardostachys jatamansi in Comparison With Diazepam in Rats. J. Med. Plants 2010; 9 (36) :169-174, URL: http://jmp.ir/article-1-260-en.html

Alessandri G, Milani C, Mancabelli L, Longhi G, Anzalone R, Lugli GA, Duranti S, Turroni F, Ossiprandi MC, van Sinderen D, Ventura M. Deciphering the Bifidobacterial Populations within the Canine and Feline Gut Microbiota. Appl Environ Microbiol. 2020 Mar 18;86(7):e02875-19. doi: 10.1128/AEM.02875-19. PMID: 32005736; PMCID: PMC7082561.

Cao F, Jin L, Gao Y, Ding Y, Wen H, Qian Z, Zhang C, Hong L, Yang H, Zhang J, Tong Z, Wang W, Chen X, Mao Z. Artificial-enzymes-armed Bifidobacterium longum probiotics for alleviating intestinal inflammation and microbiota dysbiosis. Nat Nanotechnol. 2023 Jun;18(6):617-627. doi: 10.1038/s41565-023-01346-x. Epub 2023 Mar 27. PMID: 36973397.

Grześkowiak Ł, Endo A, Beasley S, Salminen S. Microbiota and probiotics in canine and feline welfare. Anaerobe. 2015 Aug;34:14-23. doi: 10.1016/j.anaerobe.2015.04.002. Epub 2015 Apr 8. PMID: 25863311; PMCID: PMC7111060.

Pilla R, Suchodolski JS. The Gut Microbiome of Dogs and Cats, and the Influence of Diet. Vet Clin North Am Small Anim Pract. 2021 May;51(3):605-621. doi: 10.1016/j.cvsm.2021.01.002. Epub 2021 Feb 27. PMID: 33653538.

Rossi G, Pengo G, Caldin M, Palumbo Piccionello A, Steiner JM, Cohen ND, Jergens AE, Suchodolski JS. Comparison of microbiological, histological, and immunomodulatory parameters in response to treatment with either combination therapy with prednisone and metronidazole or probiotic VSL#3 strains in dogs with idiopathic inflammatory bowel disease. PLoS One. 2014 Apr 10;9(4):e94699. doi: 10.1371/journal.pone.0094699. PMID: 24722235; PMCID: PMC3983225.

Sellera FP, Fernandes MR, Sabino CP, de Freitas LM, da Silva LCBA, Pogliani FC, Ribeiro MS, Hamblin MR, Lincopan N. Effective treatment and decolonization of a dog infected with carbapenemase (VIM-2)-producing Pseudomonas aeruginosa using probiotic and photodynamic therapies. Vet Dermatol. 2019 Jan 3:10.1111/vde.12714. doi: 10.1111/vde.12714. Epub ahead of print. PMID: 30604463; PMCID: PMC6610805.

Shmalberg J, Montalbano C, Morelli G, Buckley GJ. A Randomized Double Blinded Placebo-Controlled Clinical Trial of a Probiotic or Metronidazole for Acute Canine Diarrhea. Front Vet Sci. 2019 Jun 4;6:163. doi: 10.3389/fvets.2019.00163. PMID: 31275948; PMCID: PMC6593266.

Schmitz SS. Value of Probiotics in Canine and Feline Gastroenterology. Vet Clin North Am Small Anim Pract. 2021 Jan;51(1):171-217. doi: 10.1016/j.cvsm.2020.09.011. PMID: 33187621.

Wang W, Dong H, Chang X, Chen Q, Wang L, Chen S, Chen L, Wang R, Ge S, Wang P, Li Y, Liu S, Xiong W. Bifidobacterium lactis and Lactobacillus plantarum Enhance Immune Function and Antioxidant Capacity in Cats through Modulation of the Gut Microbiota. Antioxidants (Basel). 2024 Jun 25;13(7):764. doi: 10.3390/antiox13070764. PMID: 39061833; PMCID: PMC11273429.

Yang Q, Wu Z. Gut Probiotics and Health of Dogs and Cats: Benefits, Applications, and Underlying Mechanisms. Microorganisms. 2023 Sep 29;11(10):2452. doi: 10.3390/microorganisms11102452. PMID: 37894110; PMCID: PMC10609632.

 

Customer Reviews

Be the first to write a review
0%
(0)
0%
(0)
0%
(0)
0%
(0)
0%
(0)