Skip to content
Quick view
Quick view
$167.85
$171.75
-2%
View full details Link chevron
Features Plus

✔Support healthy liver and gallbladder function.

✔Relief of indigestion, flatulence, constipation, skin complaints.

✔Supports normal detoxification processes for healthy connective tissue, muscles and joints.

✔Support respiratory tract symptoms such as irritation or coughing

✔ Support immune system health

✔Boost antioxidants to helps reduce free radicals formed in the body

✔Support immune system health.

✔Support the body’s resistance to infections

✔Support recovery from illness and infections

Ingredients Plus

Probiotic

Each gram contains: 60 million CFU of Lactobacillus Acidophilus, L Delbruekii, L Plantarum, L Rhamnosus, Bifidobacterum bifidum, Enterococcus faecium, Streptococcus salivarius. 

Immune Support

Vitamin C Ascorbic Acid Powder, Lion's Mane (Hericium erinaceus), Turkey Tail (Trametes versicolor), Chaga (Inonotus obliquus), Cordyceps (Ophiocordyceps sinensis), Olive Leaf (Olea europaea), Echinacea (Echinacea purpurea), Elecampane(Inula helenium)

Cleanse & Detox

Dandelion Leaf (Taraxacum officinale),Licorice Root (Glycyrrhiza glabra),Alfalfa (Medicago sativa), Marshmallow Root (Althaea officinalis), Red Clover (Trifolium pratense), Yellow Dock (Rumex crispus), Water(H2O), Ethanol (C2H6O)

Directions & Storage Plus

Keep out of reach of children

Store below 25 degrees Celsius.

Keep in a cool dry place out of direct sunlight.

Keep container tightly closed.

Cautions Plus

Do not give to pets while taking antibiotics.

Discontinue 7 days prior to general anaesthesia or procedure when a sedative may be administered.

Do not give during pregnancy and lactation without professional veterinary supervision. Keep out of reach of children.

The Science Plus

Azadeh, F., Gharib, F. Z., & Hosseini, S. M. (2022). Effects of glycyrrhiza glabra (licorice) root extract on the hormones, serum biochemicals, and hematological parameters in dogs with benign prostatic hyperplasia. Evidence‐Based Complementary and Alternative Medicine, 2022(1), 8962889.

Cai, X., Shao, Y., Wang, Z., Xu, Y., Ren, Z., Fu, L., & Zhu, Y. (2023). Antiviral activity of dandelion aqueous extract against pseudorabies virus both in vitro and in vivo. Frontiers in Veterinary Science, 9, 1090398.

Circosta, C., Pasquale, R. D., Palumbo, D. R., Samperi, S., & Occhiuto, F. (2006). Effects of isoflavones from red clover (Trifolium pratense) on skin changes induced by ovariectomy in rats. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 20(12), 1096-1099.

Davaatseren, M., Hur, H. J., Yang, H. J., Hwang, J. T., Park, J. H., Kim, H. J., ... & Sung, M. J. (2013). Dandelion leaf extract protects against liver injury induced by methionine-and choline-deficient diet in mice. Journal of medicinal food, 16(1), 26-33.

Micháľová A, Takáčová M, Karasová M, Kunay L, Grelová S, Fialkovičová M. Comparative Study of Classical and Alternative Therapy in Dogs with Allergies. Animals. 2022; 12(14):1832. https://doi.org/10.3390/ani12141832

Abugomaa, A., Elbadawy, M., Ishihara, Y., Yamamoto, H., Kaneda, M., Yamawaki, H., ... & Sasaki, K. (2023). Anti-cancer activity of Chaga mushroom (Inonotus obliquus) against dog bladder cancer organoids. Frontiers in Pharmacology, 14, 1159516.

Brown, D. C., & Reetz, J. (2012). Single agent polysaccharopeptide delays metastases and improves survival in naturally occurring hemangiosarcoma. Evidence‐Based Complementary and Alternative Medicine, 2012(1), 384301.

Cho HW, Choi S, Seo K, Kim KH, Jeon JH, Kim CH, Lim S, Jeong S, Chun JL. Gut microbiota profiling in aged dogs after feeding pet food contained Hericium erinaceus. J Anim Sci Technol. 2022 Sep;64(5):937-949. doi: 10.5187/jast.2022.e66. Epub 2022 Sep 30. PMID: 36287790; PMCID: PMC9574611.

Daniel S. Gordon, Adam J. Rudinsky, Julien Guillaumin, Valerie J. Parker, Karina J. Creighton,Vitamin C in Health and Disease: A Companion Animal Focus,Topics in Companion Animal Medicine,Volume 39,2020,100432,ISSN 1938-9736,https://doi.org/10.1016/j.tcam.2020.100432.

Friedman M. Mushroom Polysaccharides: Chemistry and Antiobesity, Antidiabetes, Anticancer, and Antibiotic Properties in Cells, Rodents, and Humans. Foods. 2016; 5(4):80. https://doi.org/10.3390/foods5040080

Jung, Y. C., Kim, H. W., Min, B. K., Cho, J. Y., Son, H. J., Lee, J. Y., ... & Lee, H. W. (2019). Inhibitory effect of olive leaf extract on obesity in high-fat diet-induced mice. in vivo, 33(3), 707-715.

Khan, Md. Asaduzzaman; Tania, Mousumi; Zhang, Dianzheng; and Chen, Hanchun, "Cordyceps Mushroom: a Potent Anticancer Nutraceutical" (2010). PCOM Scholarly Papers. 373.https://digitalcommons.pcom.edu/scholarly_papers/373

Kimura, Y., & Sumiyoshi, M. (2009). Olive leaf extract and its main component oleuropein prevent chronic ultraviolet B radiation-induced skin damage and carcinogenesis in hairless mice. The journal of nutrition, 139(11), 2079-2086.

Liu, J. Y., Feng, C. P., Li, X., Chang, M. C., Meng, J. L., & Xu, L. J. (2016). Immunomodulatory and antioxidative activity of Cordyceps militaris polysaccharides in mice. International Journal of Biological Macromolecules, 86, 594-598.

Liu, RM., Zhang, XJ., Liang, GY. et al. Antitumor and antimetastatic activities of chloroform extract of medicinal mushroom Cordyceps taii in mouse models. BMC Complement Altern Med 15, 216 (2015). https://doi.org/10.1186/s12906-015-0762-9

Mikami, T., Kim, J., Park, J., Lee, H., Yaicharoen, P., Suidasari, S., ... & Yamauchi, K. (2021). Olive leaf extract prevents obesity, cognitive decline, and depression and improves exercise capacity in mice. Scientific reports, 11(1), 12495.

Menezes, R. C. R., Peres, K. K., Costa-Valle, M. T., Faccioli, L. S., Dallegrave, E., Garavaglia, J., & Dal Bosco, S. M. (2022). Oral administration of oleuropein and olive leaf extract has cardioprotective effects in rodents: A systematic review. Revista Portuguesa de Cardiologia, 41(2), 167-175.

Park, J. H., Jung, J. H., Yang, J. Y., & Kim, H. S. (2013). Olive leaf down-regulates the oxidative stress and immune dysregulation in streptozotocin-induced diabetic mice. Nutrition research, 33(11), 942-951.

Tong, J. O. P. (2021). Does turkey tail as an adjuvant therapy improve the quality of life of canine lymphoma patients?. Veterinary Evidence, 6(3).

Wainstein, J., Ganz, T., Boaz, M., Bar Dayan, Y., Dolev, E., Kerem, Z., & Madar, Z. (2012). Olive leaf extract as a hypoglycemic agent in both human diabetic subjects and in rats. Journal of medicinal food, 15(7), 605-610.

Xiao, J. H., Xiao, D. M., Chen, D. X., Xiao, Y., Liang, Z. Q., & Zhong, J. J. (2012). Polysaccharides from the Medicinal Mushroom Cordyceps taii Show Antioxidant and Immunoenhancing Activities in a D‐Galactose‐Induced Aging Mouse Model. Evidence‐based Complementary and Alternative Medicine, 2012(1), 273435.

Xun, C., Shen, N., Li, B., Zhang, Y., Wang, F., Yang, Y., ... & Thompson, J. S. (2008). Radiation mitigation effect of cultured mushroom fungus Hirsutella Sinensis (CorImmune) isolated from a Chinese/Tibetan herbal preparation–Cordyceps Sinensis. International Journal of Radiation Biology, 84(2), 139-149.

Alessandri G, Milani C, Mancabelli L, Longhi G, Anzalone R, Lugli GA, Duranti S, Turroni F, Ossiprandi MC, van Sinderen D, Ventura M. Deciphering the Bifidobacterial Populations within the Canine and Feline Gut Microbiota. Appl Environ Microbiol. 2020 Mar 18;86(7):e02875-19. doi: 10.1128/AEM.02875-19. PMID: 32005736; PMCID: PMC7082561.

Cao F, Jin L, Gao Y, Ding Y, Wen H, Qian Z, Zhang C, Hong L, Yang H, Zhang J, Tong Z, Wang W, Chen X, Mao Z. Artificial-enzymes-armed Bifidobacterium longum probiotics for alleviating intestinal inflammation and microbiota dysbiosis. Nat Nanotechnol. 2023 Jun;18(6):617-627. doi: 10.1038/s41565-023-01346-x. Epub 2023 Mar 27. PMID: 36973397.

Grześkowiak Ł, Endo A, Beasley S, Salminen S. Microbiota and probiotics in canine and feline welfare. Anaerobe. 2015 Aug;34:14-23. doi: 10.1016/j.anaerobe.2015.04.002. Epub 2015 Apr 8. PMID: 25863311; PMCID: PMC7111060.

Pilla R, Suchodolski JS. The Gut Microbiome of Dogs and Cats, and the Influence of Diet. Vet Clin North Am Small Anim Pract. 2021 May;51(3):605-621. doi: 10.1016/j.cvsm.2021.01.002. Epub 2021 Feb 27. PMID: 33653538.

Rossi G, Pengo G, Caldin M, Palumbo Piccionello A, Steiner JM, Cohen ND, Jergens AE, Suchodolski JS. Comparison of microbiological, histological, and immunomodulatory parameters in response to treatment with either combination therapy with prednisone and metronidazole or probiotic VSL#3 strains in dogs with idiopathic inflammatory bowel disease. PLoS One. 2014 Apr 10;9(4):e94699. doi: 10.1371/journal.pone.0094699. PMID: 24722235; PMCID: PMC3983225.

Sellera FP, Fernandes MR, Sabino CP, de Freitas LM, da Silva LCBA, Pogliani FC, Ribeiro MS, Hamblin MR, Lincopan N. Effective treatment and decolonization of a dog infected with carbapenemase (VIM-2)-producing Pseudomonas aeruginosa using probiotic and photodynamic therapies. Vet Dermatol. 2019 Jan 3:10.1111/vde.12714. doi: 10.1111/vde.12714. Epub ahead of print. PMID: 30604463; PMCID: PMC6610805.

Shmalberg J, Montalbano C, Morelli G, Buckley GJ. A Randomized Double Blinded Placebo-Controlled Clinical Trial of a Probiotic or Metronidazole for Acute Canine Diarrhea. Front Vet Sci. 2019 Jun 4;6:163. doi: 10.3389/fvets.2019.00163. PMID: 31275948; PMCID: PMC6593266.

Schmitz SS. Value of Probiotics in Canine and Feline Gastroenterology. Vet Clin North Am Small Anim Pract. 2021 Jan;51(1):171-217. doi: 10.1016/j.cvsm.2020.09.011. PMID: 33187621.

Wang W, Dong H, Chang X, Chen Q, Wang L, Chen S, Chen L, Wang R, Ge S, Wang P, Li Y, Liu S, Xiong W. Bifidobacterium lactis and Lactobacillus plantarum Enhance Immune Function and Antioxidant Capacity in Cats through Modulation of the Gut Microbiota. Antioxidants (Basel). 2024 Jun 25;13(7):764. doi: 10.3390/antiox13070764. PMID: 39061833; PMCID: PMC11273429.

Yang Q, Wu Z. Gut Probiotics and Health of Dogs and Cats: Benefits, Applications, and Underlying Mechanisms. Microorganisms. 2023 Sep 29;11(10):2452. doi: 10.3390/microorganisms11102452. PMID: 37894110; PMCID: PMC10609632.

 

Customer Reviews

Be the first to write a review
0%
(0)
0%
(0)
0%
(0)
0%
(0)
0%
(0)