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$49.95
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Features Plus

• Contains multiple probiotic strains (7 strains) to help improve intestinal barrier function and support a healthy immune system.

• Improve intestinal barrier function

• Inhibit mast cell activation

• Positively influence the immune system decreasing lipopolysaccharide (LPS) load

• Reduce susceptibility to suboptimal mood

• Support a healthy immune system

• Support general health and wellbeing

Ingredients Plus

Each gram contains: 60 million CFU of Lactobacillus Acidophilus, L Delbruekii, L Plantarum, L Rhamnosus, Bifidobacterum bifidum, Enterococcus faecium, Streptococcus salivarius. 

Directions & Storage Plus

Store in a cool dark place or refrigerate.

Give your pet a loading dose of double the daily dose for 10 days before reducing to the daily dose.

Give according to your pet’s weight:

0-5kg - 1/4 teaspoon daily

6-15kg - 1/2 teaspoon daily

15-25kg - 1 teaspoon daily

26-35kg - 1 and 1/2 teaspoons

36-45kg - 2 teaspoons daily

Over 45kg- 2.5 teaspoons daily

Cautions Plus

Do not give to pets while taking antibiotics.

The Science Plus

Alessandri G, Milani C, Mancabelli L, Longhi G, Anzalone R, Lugli GA, Duranti S, Turroni F, Ossiprandi MC, van Sinderen D, Ventura M. Deciphering the Bifidobacterial Populations within the Canine and Feline Gut Microbiota. Appl Environ Microbiol. 2020 Mar 18;86(7):e02875-19. doi: 10.1128/AEM.02875-19. PMID: 32005736; PMCID: PMC7082561.

Cao F, Jin L, Gao Y, Ding Y, Wen H, Qian Z, Zhang C, Hong L, Yang H, Zhang J, Tong Z, Wang W, Chen X, Mao Z. Artificial-enzymes-armed Bifidobacterium longum probiotics for alleviating intestinal inflammation and microbiota dysbiosis. Nat Nanotechnol. 2023 Jun;18(6):617-627. doi: 10.1038/s41565-023-01346-x. Epub 2023 Mar 27. PMID: 36973397.

Grześkowiak Ł, Endo A, Beasley S, Salminen S. Microbiota and probiotics in canine and feline welfare. Anaerobe. 2015 Aug;34:14-23. doi: 10.1016/j.anaerobe.2015.04.002. Epub 2015 Apr 8. PMID: 25863311; PMCID: PMC7111060.

Pilla R, Suchodolski JS. The Gut Microbiome of Dogs and Cats, and the Influence of Diet. Vet Clin North Am Small Anim Pract. 2021 May;51(3):605-621. doi: 10.1016/j.cvsm.2021.01.002. Epub 2021 Feb 27. PMID: 33653538.

Rossi G, Pengo G, Caldin M, Palumbo Piccionello A, Steiner JM, Cohen ND, Jergens AE, Suchodolski JS. Comparison of microbiological, histological, and immunomodulatory parameters in response to treatment with either combination therapy with prednisone and metronidazole or probiotic VSL#3 strains in dogs with idiopathic inflammatory bowel disease. PLoS One. 2014 Apr 10;9(4):e94699. doi: 10.1371/journal.pone.0094699. PMID: 24722235; PMCID: PMC3983225.

Sellera FP, Fernandes MR, Sabino CP, de Freitas LM, da Silva LCBA, Pogliani FC, Ribeiro MS, Hamblin MR, Lincopan N. Effective treatment and decolonization of a dog infected with carbapenemase (VIM-2)-producing Pseudomonas aeruginosa using probiotic and photodynamic therapies. Vet Dermatol. 2019 Jan 3:10.1111/vde.12714. doi: 10.1111/vde.12714. Epub ahead of print. PMID: 30604463; PMCID: PMC6610805.

Shmalberg J, Montalbano C, Morelli G, Buckley GJ. A Randomized Double Blinded Placebo-Controlled Clinical Trial of a Probiotic or Metronidazole for Acute Canine Diarrhea. Front Vet Sci. 2019 Jun 4;6:163. doi: 10.3389/fvets.2019.00163. PMID: 31275948; PMCID: PMC6593266.

Schmitz SS. Value of Probiotics in Canine and Feline Gastroenterology. Vet Clin North Am Small Anim Pract. 2021 Jan;51(1):171-217. doi: 10.1016/j.cvsm.2020.09.011. PMID: 33187621.

Wang W, Dong H, Chang X, Chen Q, Wang L, Chen S, Chen L, Wang R, Ge S, Wang P, Li Y, Liu S, Xiong W. Bifidobacterium lactis and Lactobacillus plantarum Enhance Immune Function and Antioxidant Capacity in Cats through Modulation of the Gut Microbiota. Antioxidants (Basel). 2024 Jun 25;13(7):764. doi: 10.3390/antiox13070764. PMID: 39061833; PMCID: PMC11273429.

Yang Q, Wu Z. Gut Probiotics and Health of Dogs and Cats: Benefits, Applications, and Underlying Mechanisms. Microorganisms. 2023 Sep 29;11(10):2452. doi: 10.3390/microorganisms11102452. PMID: 37894110; PMCID: PMC10609632.