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Features Plus

• Herbal blend with inclusion of plant-based digestive enzymes formulated to support the breakdown of yeast and support the body to eliminate toxins associated with yeast breakdown. It has been designed to support dogs suffering from yeast overgrowth and support healthy immune response, gut and skin health.

• Combination of herbs traditionally used in Western herbal medicine to helps decrease/reduce/relieve symptoms of fungal infection, relieve inflammation, support healthy digestive, liver function and maintain healthy skin and coat.

• Olive leaf is included to reduce free radicals formed in the body and help reduce free radical damage to body cells

• Maintain/support general health and wellbeing

• To support the body’s resistance to infections of all kinds.

• Reduce topical skin lesions and aid in wound healing.

Ingredients Plus

Golden Seal (Hydrastis canadensis), Pau D'Arco (Handroanthus impetiginosus), Milk Thistle (Silybum marianum), Thuja (Thuja occidentalis) , Calendula (Calendula officinalis), Barberry (Berberis vulgaris), Echinacea (Echinacea purpurea), Ginger(Zingiber officinale), Olive Leaf (Olea europaea), Fennel (Foeniculum vulgare), Garlic (Allium sativum), Digestive enzymes (Alpha amylase, acid protease, cellulase, lactase, lipase).

Directions & Storage Plus

Give according to your pet’s weight or as recommended by your animal healthcare professional. We recommend giving with small portion of daily food intake, separate from normal meal.

Not suitable for cats.

Dogs:

0-5kg - 1/4 teaspoon twice daily

6-15kg - 1/2 teaspoon twice daily

15-25kg - 1 teaspoon twice daily

26-35kg - 1 and 1/2 teaspoons twice daily

36-45kg - 2 teaspoons twice daily

Over 45kg- 3 teaspoons twice daily

Store below 25 degrees Celsius. Keep in a cool dry place out of direct sunlight. Keep container tightly closed.

Keep out of reach of children.

Cautions Plus

Discontinue 7 days prior to general anaesthesia or procedure when a sedative may be administered.

Do not give during pregnancy and lactation without professional veterinary supervision.

The Science Plus

Efstratiou, E., Hussain, A. I., Nigam, P. S., Moore, J. E., Ayub, M. A., & Rao, J. R. (2012). Antimicrobial activity of Calendula officinalis petal extracts against fungi, as well as Gram-negative and Gram-positive clinical pathogens. Complementary Therapies in Clinical Practice, 18(3), 173-176.

Gao Y, Swiggart E, Wolkiewicz K, Liyanapathiranage P, Baysal-Gurel F, Avin FA, Lopez EFP, Jordan RT, Kellogg J, Burkhart EP. Goldenseal (Hydrastis canadensis L.) Extracts Inhibit the Growth of Fungal Isolates Associated with American Ginseng (Panax quinquefolius L.). Molecules. 2024; 29(3):556. https://doi.org/10.3390/molecules29030556

Gharibpour, F., Shirban, F., Bagherniya, M., Nosouhian, M., Sathyapalan, T., & Sahebkar, A. (2021). The effects of nutraceuticals and herbal medicine on Candida albicans in oral candidiasis: a comprehensive review. Pharmacological Properties of Plant-Derived Natural Products and Implications for Human Health, 225-248.

Kazemipoor, M., Fadaei Tehrani, P., Zandi, H., & Golvardi Yazdi, R. (2021). Chemical composition and antibacterial activity of Berberis vulgaris (barberry) against bacteria associated with caries. Clinical and experimental dental research, 7(4), 601-608.

Momeni, M. K., Bameri, O., Ghafari, M., Saravani, S., & Javadian, F. (2021). Evaluation of antifungal activity of medicinal plant extracts on candida albicans. Journal of Obstetrics, Gynecology and Cancer Research, 6(2), 50-56.

Nasrollahi Z, Abolhasannezhad M. Evaluation of the antifungal activity of olive leaf aqueous extracts against Candida albicans PTCC-5027. Curr Med Mycol. 2015 Dec;1(4):37-39. doi: 10.18869/acadpub.cmm.1.4.37. PMID: 28681003; PMCID: PMC5490280.

Rahimi Kakolaki, M., Omidi, A., Rasooli, A., & Shekarforoush, S. S. (2024). In vitro antifungal activity of barberry fruit extract (Berberis spp.) against Fusarium spp. Journal of Horticulture and Postharvest Research, 7(Special Issue-Postharvest Technologies), 47-60.

Saffari, E., Mohammad-Alizadeh-Charandabi, S., Adibpour, M., Mirghafourvand, M., & Javadzadeh, Y. (2017). Comparing the effects of Calendula officinalis and clotrimazole on vaginal Candidiasis: A randomized controlled trial. Women & health, 57(10), 1145-1160.

Sudjana, A. N., D’Orazio, C., Ryan, V., Rasool, N., Ng, J., Islam, N., ... & Hammer, K. A. (2009). Antimicrobial activity of commercial Olea europaea (olive) leaf extract. International journal of antimicrobial agents, 33(5), 461-463. Chicago

Vinola, S. M., Sekar, M., Renganathan, S. K., & Dhiraviam, S. (2021). Comparative Evaluation of Calendula officinalis and 2% Chlorhexidine against Enterococcus faecalis and Candida albicans. Journal of Interdisciplinary Dentistry, 11(3), 119-123.

Chicago

Zorić, N., Kopjar, N., Kraljić, K., Oršolić, N., Tomić, S., & Kosalec, I. (2016). Olive leaf extract activity against Candida albicans and C. dubliniensis–the in vitro viability study. Acta Pharmaceutica, 66(3), 411-431.